I haven't updated my list of currently followed podcasts in a while. That list has really shrunk. At current, there are only two that update weekly that I don't really ever miss an episode of.
My Brother, My Brother and Me
- Of course. I've mentioned it before, as have others, but it's a comedy/advice podcast almost in the vein of a Dear Abby sort of thing. They take questions from listeners and answer them. They also take wretched filth from Yahoo! Answers and rip on it. It's become my favorite podcast, hands down.
- This is the only gaming related podcast I can do anymore. Probably because they spend more time just shooting the shit about absolutely anything and everything else. Also because of Dan Ryckert. It's not technically a comedy podcast, but it makes me laugh pretty regularly. I enjoy it a lot.
Those are the only two I hit up without delay whenever they update anymore. After that, I tend to go for The Adventure Zone
(D&D podcast starring the MBMBaM guys), Eye On Basketball
(CBS's basketball podcast), Jalen & Jacoby
(Grantland's best and brightest talk basketball and sometimes hip-hop) and Judge John Hodgman
(couldn't be more self explanatory). Anything else I currently listen to tends to be far more sporadic anymore.